Drinking Water as a Proportion of Total Human Exposure to Volatile N ‐Nitrosamines
نویسندگان
چکیده
منابع مشابه
Ingestion Exposure to Nitrosamines in Chlorinated Drinking Water
OBJECTIVES N-Nitrosodimethylamine (NDMA) is classified as a probable human carcinogen by the United States Environmental Protection Agency (US EPA) and is formed during the chlorination of municipal drinking water. In this study, selected nitrosamines were measured in chlorinated drinking water collected from Chuncheon, Kangwon-do, Republic of Korea, and a risk assessment for NDMA was conducted...
متن کاملQuantitation of urinary volatile nitrosamines from exposure to tobacco smoke.
A sensitive and selective method was developed and validated to detect six volatile nitrosamines (N-nitrosodimethylamine, N-nitrosomethylethylamine, N-nitrosodiethylamine, N-nitrosopiperidine, N-nitrosopyrrolidine and N-nitrosomorpholine) in human urine. This method uses a liquid-liquid extraction cartridge followed by analysis with gas chromatography-tandem mass spectrometry (GC-MS-MS) and qua...
متن کاملAbsence of Volatile Nitrosamines in Human Feces1
Using a method for nitrosamine analysis that gives high recovery values and that is free from artifactual synthesis of nitrosamines, we have shown that human feces do not contain volatile nitrosamines (detection limit, 0.1 to 0.5 /ng/kg). We also showed that nitrosation reactions are not catalyzed by fecal organisms. Following a 2-day anaerobic incubation of feces with either a secondary aminé...
متن کاملFormation of N -Nitrosamines in Drinking Water Sources: Case Studies From Western Australia
The occurrence and formation of N-nitrosamines in water supplies is of concern to the water industry, as N-nitrosamines have been reported to be carcinogenic, mutagenic, and/or teratogenic. The US Environmental Protection Agency’s (USEPA’s) Integrated Risk Information System indicates that N-nitrosodimethylamine (NDMA) is a probable human carcinogen (USEPA 1997). Other N-nitrosamines typically ...
متن کاملIncrease in human exposure to methylamine precursors of N-nitrosamines after eating fish.
Consumption of fish has been encouraged recently because it may prevent mortality due to heart disease. Fish contains methylamines, which are precursors of N-nitrosamines. Nitrosamines can act as potent carcinogens in a wide variety of animal species, and there is no reason to assume that humans are resistant. Human subjects (n = 5) ingested a diet of known methylamine content for 2 days. On Da...
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ژورنال
عنوان ژورنال: Risk Analysis
سال: 2013
ISSN: 0272-4332,1539-6924
DOI: 10.1111/risa.12070